The best and the rest of the Web

Humour
The Bastard Operator From Hell - This is as close to job satisfaction as I could ever get.
Herd of Sheep - Too damn close to real English newspapers for words.
Critical Miss - Technically should go under Roleplaying, but as it's both it goes here.
Acts of Gord - Just read it.

Computing
The Register - Up to date UK computing news site, also hosts the 2000 and 2001 Bastard Operator From Hell archives.
Style Sheets - A most excellent tutorial on using CSS in your HTML documents. Read and learn the folly of <font>.
Topica - An alternative to the hideous, bloated monstrosity that is Yahoo Groups.
w3c - The Web Standards Organisation.

Roleplaying
White Wolf - Makers of some of the better RPG's out there. And Vampire: The Pretention.
Wolf Spoor - The ultimate news and fan site for White Wolf and Sword & Sorcery Studios.
The Wraith Project - I write for them, I have to give them a link!
Black Hat Matt - A kindred spirit in the art of GMing.
Nightfall Games - SLA Industries is one of the many other games I love. These guys make it. Worship the game.
Blackjack's Shadowrun Page - Resources for Shadowrun that can be adapted to other games, and another evil GM.
Pandora's Box of SLA - A huge collection of stuff for SLA Industries.
SLA-net - An in-character website including BPN's and squad e-mail.
SLAIndustries.net - A community site in a similar vein to the various Planet sites out there.
WolfSpoor - A similar community site for White Wolf Games Studio

General
Warren Ellis - One of the better comics writers out there.
Staffordshire University - The place that gave me my degree.
Stephen's Guide to the Logical Fallacies - Things not to do in a debate, and things to call your opponent on.